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Posts Tagged ‘fertility nutrition’

Female Fertility

The IVF Cycle

Although a woman may need just one or two therapies to restore fertility, it’s possible that several different types of treatment may be needed before she is able to conceive. Other techniques are sometimes used in an IVF cycle, such as:

  • Intracytoplasmic sperm injection (ICSI). In ICSI, a single healthy sperm is injected directly into a mature egg. ICSI is often used when semen quality is a problem there are few sperm, or if fertilisation attempts during prior IVF cycles failed.
  • Assisted hatching. This technique attempts to assist the implantation of the embryo into the lining of the uterus by opening the outer covering of the embryo (hatching).
  • Donor eggs or sperm. Most ART is done using the woman’s own eggs and her partner’s sperm. However, if there are severe problems with either the eggs or sperm, you may choose to use eggs, sperm or embryos from a known or anonymous donor.
  • Gestational carrier. Women who do not have a functional uterus or for whom pregnancy poses a serious health risk might choose IVF using a gestational carrier. In this case, the couple’s embryo is placed in the uterus of the carrier for pregnancy.
Complete Care System

Complete Care System

Complications of female infertility treatment

Complications of female infertility treatment may include: Multiple pregnancy – Ovarian hyperstimulation syndrome (OHSS) – Bleeding or infection – Premature delivery or low birth weight – Birth defects.

Infertility for women due to ovulation disorders are supported greatly by the Naturopathic Portfolio for female fertility. We use the functional  approach at Susannah Makram Clinics.

This is because fertility drugs – that regulate or induce ovulation – are the main treatment for women who are infertile due to ovulation disorders.

Hormone Imbalance

Hormone Imbalance

 

In general, they work like the natural hormones — follicle-stimulating hormone (FSH) and luteinizing hormone (LH) — to trigger ovulation.

They are also used in women who ovulate to try to stimulate a better egg or an extra egg or eggs. Eg. fertility drugs may include: Metformin. Metformin (Glucophage, others) is used when insulin resistance is a known or suspected cause of infertility, usually in women with a diagnosis of PCOS. Metformin helps improve insulin resistance, which can make ovulation more likely to occur.

REDUCING RISK FACTORS AND WEIGHT LOSS FOR FERTILITY

Polycystic ovary syndrome (PCOS) is a common endocrine condition with reproductive and metabolic consequences, including anovulation, infertility and an increased prevalence of diabetes mellitus. Obesity, central obesity and insulin resistance are strongly implicated in its aetiology. Reduction of these risk factors should be a central treatment focus. Short-term weight loss has been consistently successful in reducing insulin resistance and restoring ovulation and fertility.

FIND OUT MORE ABOUT FERTILITY TREATMENT ROUTES AND HOW SUPPORTING LIFESTYLE CHANGES CAN HELP COUPLES TODAY.

 

TRYING TO GET PREGNANT

Pregnancy Tips

We’re all trying to keep our bodies fit and toned. We all want a good sex life. Sometimes the best we can hope for is a sex drive. However, there comes a time when we start to think about the possibility of starting a family. Starting a family or adding to our small family. We might only be thinking about it but the thoughts are inevitable.

fertility nutrition

fertility nutrition

 

So, it is that we ask how our modern lifestyle – our environment and the choices we’re making are going to impact our fertility journey. Does it stop at our choices? 

Fertility nutrition is a lifestyle. Your fertility journey isn’t the same as every other couple. Susannah sees mothers who want to add to their beautiful and healthy family. She sees couples who’ve been through fertility testing and fertility treatment. This includes Assisted Reproductive Technology ART -most commonly IVF. Susannah sees couples who place value on a holistic and natural approach. Balance within our bodies helps create the right environment to step into our life’s journey.

 

Trying To Get Pregnant

Trying To Get Pregnant

Being present in that health journey means offering functional and practical advice. Being relaxed is one of the things couples trying for a baby hear constantly. It’s also one of least helpful pregnancy tips!

Trying to get pregnant

Susannah answers readers and couples’  questions on fertility. Couples trying to get pregnant ask pertinent lifestyle questions. Wanting for a healthy pregnancy journey starts with questions. From ovulation to birth control to the most effective sex positions to “fertility windows”.

Getting pregnant can prove to be a minefield of facts, fads and questions. They can send our stress levels through the roof.  Ironically this can do more harm than good when it comes to improving chances of conception.

To help clear the confusion, Get The Gloss asked Naturopath and fertility nutrition expert Susannah Makram for her top tips for getting pregnant. Whether you are wondering when you are most fertile or how to work out the inner workings of your ovulation cycle, here are Susannah’s 15 key tips to bear in mind should you be on the path to pregnancy.

We spend our whole lives taking take of our body for us. Suddenly we consider another journey for this amazing biological wonder. It’s a life change that’s changing us and challenging us in different ways in modern times.

Read the full article here

Getting Pregnant – Facts For NOW

Diet for pregnancy

diet for pregnancy

diet for pregnancy

With 1 IN 6 Couples currently experiencing difficulty getting pregnant, Get The Gloss caught up with their Expert in Naturopathic Nutrition and osteopathy. SUSANNAH MAKRAM covers the facts we should all know before embarking on the road to fertility.

Infertility is a rising problem. According to recent statistics, ‘one in six couples has problems starting a family, with the number of couples seeking medical help having risen dramatically.’  [tweetthis hidden_hashtags=”#nutrition”]What you need to know now if you’re thinking about getting #pregnant[/tweetthis]

Fertility and lifestyle

Most experts suggest these increasing problems with couples trying to get pregnant are due to larger amounts of environmental chemicals. These chemicals affect the body’s hormones, in men and women. Also, societal and cultural changes see more women choosing to delay starting a family until established in their careers. The older both men and women become, the more likely it is to encounter difficulties conceiving, for the woman to become pregnant.

The problem however, is that unless specifically trying to get pregnant, most women don’t know enough about fertility and the factors that can affect our chances. So, with the aim of getting us all a little more clued-up we reached out to fertility and nutrition expert, Susannah Makram, for a little more information on the possibilities and problems getting pregnant.

Read the full article here

Horse Fertility Nutrition, Personalised

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Horse Fertility Nutrition, Personalised

The horse genome was sequenced in 2007 with the final report published in late 2009.
This research enables scientists to better understand the molecular and biological processes responsible for equine health and performance. As a Naturopath and as an osteopath, I use a functional approach that resonates with my equine osteopathic and veterinary colleagues.

Horse nutrition

Horse fertility nutrition, is personalised as it is for humans. It teaches us a lot about this exact science of eating for health. This approach enables us to learn from research. We can apply what we learn accordingly for personalised fertility nutrition for humans.

Treating the cause of reproductive challenges or fertility concerns, as with complex cases treated at Susannah Makram clinics, requires an integrative healthcare approach. It is also how I came across special laboratory investigations or tests that we now use to choose the best treatment and optimise efficacy of treatment. This functional healthcare model relies on careful use of accurate methods of laboratory investigations when results impact nutritional therapy. Good nutrition is the cornerstone to healthy weight management in pre-conceptual care and treatment of factors affecting fertility in males and females and throughout pregnancy.

I was introduced to the latest advancement to male fertility testing by an avid horse breeder in Sussex, where I went to boarding school, enjoyed the stables and grounds. For many hours I blissfully recreated my childhood in Dhahran, Saudi Aramco horse riding at the Hobby Farm.

Semen Analysis And Stallion Fertility

The Society for Theriogenology has established guidelines for classifying stallions as to breeding potential. For a satisfactory rating, the Society requires that light-breed stallions ejaculate at least four billion total sperm in the first ejaculate after a period (typically one week) of sexual rest. The second ejaculate, collected about an hour after the first, should contain at least two billion total sperm.

Semen analysis
Sperm count
Sperm motility
Sperm morphology

These have typically been carried out on male human patients whereby; the results of the above show good fertility readings, the partner is similarly ‘fertile’ and after the couple undergo IVF cycles they are couple are given the diagnosis of: ‘unexplained infertility’.

My interest in treating the cause of infertility led me to this discovery – Sophisticated tests that can be performed on stallions:

Karyotype Analysis
Chemical Analysis of Seminal Plasma
Transmission Electron Microscopic Analysis of Sperm
Sperm Chromatin Structure Assay–The sperm chromatin structure assay is a procedure that has been developed to evaluate the structural integrity of sperm chromatin. This assay defines abnormal chromatin structure as a heat- or acid-induced susceptibility to DNA denaturation (destruction of the substance). Lower fertility occurs when greater sperm denaturation is found. The sperm chromatin structure assay may have potential for identifying some stallions as subfertile when routine breeding soundness examination fails to do so.
Antisperm Antibody Tests
Hormonal Assays

Sperm Chromatin Structure Assay is of interest to me as it offers information regarding the quality of sperm and this can only be improved upon by lifestyle changes. The right nutrients taken through diet and supplementation (for the first 2-3 months, dependent on the percentage of sperm DNA damage) reverse the damage.
Fish oil, for example, improves the quality of shipped semen in horses. Supplementing with natural-source vitamin E, a potent antioxidant, improves sperm quality also. There are several types of antioxidants: enzymatic antioxidants that are synthesized in the body and non-enzymatic, or nutritional, antioxidants like vitamin E, vitamin C, and selenium that are provided in a horse’s diet. Such antioxidants increase libido and semen quality in stallions and positively affect fertility in mares.

The genomic revolution has propelled the development of several new technologies in science and in the health industry. The data such technology provides is game changing in our industry when knowledge is effectively and is used to its full potential to translate science into practical and effective clinical nutritional therapy.
For horses this means that a report can be produced that measures the bioavailability of various nutrients to find out what works best for the animal.
Measuring the bioavailability of nutrients, as this is as unique to every human as is their DNA, is an invaluable tool we are using now at Susannah Makram Clinics to improve quality of life in humans. Prevention is better than cure.
Genetic screening tests for mares can account for primary infertility and reduced fertility rates.

Primary infertility in mares

The most commonly encountered chromosomal abnormality in horses, XO Gonadal Dysgenesis, was first described 1975. The condition is similar to Turner syndrome in human females. Prognosis for fertility is extremely poor. The syndrome has been diagnosed in diverse horse breeds throughout the world including Thoroughbred, Arabian, Welsh Pony, Tennessee Walking Horse, Standardbred, American Saddlebred, Paso Fino, Belgian, Quarter Horse, Appaloosa, as well as in grade horses.
The second most common finding in infertile mares with inactive gonads is the karyotype of a male horse (64,XY)(XY Gonadal Dysgenesis, XY Sex Reversal, Testicular Feminization). The problem may have a genetic origin. It has been encountered in Arabians, Thoroughbreds, Quarter Horses, Appaloosas, Morgans, Standardbreds and a pony of unknown pedigree. Fertility has been reported in XY mares, but is extremely infrequent.
Reduced fertility
The first example – that has been associated with chromosomal rearrangements called balanced reciprocal translocations – has been described in a mare and it is anticipated that others will be identified as the power of karyotyping tests to diagnose the basis of certain kinds of infertility becomes more widely known.

Weight of horse

Overweight mares have reduced fertility just as overweight stallions do. This is why DNA testing for weight management improves the overall health of humans and horses alike. Obesity increases risk of cardiovascular disease and can lead to insulin re that affects the male’s ability to maintain an erection for example.
Obesity can lead to insulin resistance in females that has correlations to PCOS that can cause fertility concerns or infertility.

For both horses and humans a bristle style cheek swaps is sufficient to collect the required DNA sample to test for the genes that impact metabolism and exercise.
A tailored nutritional plan that prescribes the right amount of food energy sources in the right measure in order that body fat composition is reduced in cell size and number than then be applied accurately.

Potential Future Applications
Sequencing the horse genome is just the start. The future will be how to use it in more and more effective ways for the benefits of the horse, the overall health and wellbeing.
The science of nutrigenomics looks to find out how diet affects gene expression and hence metabolism. Reversing (sperm) DNA damage using nutritional therapy and supplementation improves fertility rates, offers reason for previously diagnosed ’unexplained infertility’ and guides humans to the right fertility treatment where they have the best chances of conceiving.
It is already known that food components like fats, vitamins or minerals not only provide vital nutrition for the body but also affect the way genes are expressed. Selenium, for example, a trace mineral, is known to be essential for fertility. This would be a very useful area for equine science to investigate, in light of how this has progressed fertility rates and outcomes in other species, to include humans.

Susannah is a Naturopathic Doctor of Nutrition with a clinical background in osteopathy www.susannahmakram.com

When IVF Fails

Posted on: by Susannah

Infertility Treatment

INFERTILITY CARE PATHWAYS depend on 1) WHEN infertility diagnosis made (2) age (3) your partner’s age (4) many personal preferences. When IVF fails we reassess these causes. At Susannah Makram Clinics we view infertility as a complete care pathway. That this may be supported by our individual body wellness is where we come in.

When IVF Fails

When IVF fails your decision to go ahead with the same treatment for infertility is usually put into question. This is a natural reaction to have.

In vitro fertilisation (IVF) is the most common ART technique. When IVF fails, the decision to continue with another IVF cycle, at the earliest possible time, is not one to take lightly. Assisted reproductive technology (ART) is any fertility treatment in which the egg and sperm are handled.
IVF involves stimulating and retrieving multiple mature eggs from a woman, fertilising them with a man’s sperm in a dish in a lab, and implanting the embryos in the uterus three to five days after fertilisation.

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When IVF Fails

IVF Success Rates

IVF-conceived babies now account for 2% all babies born in the UK.      [tweetthis]IVF-conceived babies now account for 2% all babies born in the UK[/tweetthis]

The success rate of ART is lower after age 35. This is according to new figures on infertility treatment us and outcomes. these figures are released annually by the Human Fertilisation and Embryology Authority (HFEA).

When choosing a fertility clinic carrying out IVF treatment The HFEA presents success rates for every licensed clinic.

Some women need just one or two therapies to restore fertility. It is possible that several different types of treatment may be needed before you are able to conceive.

GENETIC and CHROMOSOMAL issues causing FAILURE OF IMPLANTATION in IVF – The high rate of chromosomal abnormalities in human embryos.

  • As women age, the incidence of chromosomal abnormalities in mature eggs increases significantly. Studies have shown that starting in early 30s, the rate of chromosomal abnormalities in human eggs (and therefore in human embryos) starts to increase significantly.
  • The rate continues to increase with advancing female age. By mid-40s a very high percentage of human embryos are chromosomally abnormal (over 75%).
  • It’s believed that this is mainly due to problems with the spindle apparatus in the egg nucleus. The spindle is involved with properly lining up and segregating the chromosomes as the egg matures at the time of ovulation.
  • Older eggs have an inefficient spindle apparatus that does not line up the chromosome pairs properly. “Mistakes” are made when splitting pairs of chromosomes. This leads to eggs that don’t have the proper balance of 23 chromosomes – and will result in a chromosomally abnormal embryo if fertilised.
  • It has been shown that about 1% to 2% of human sperm are chromosomally abnormal on average – as compared to about 20% to 90% of human eggs (depending on female age).
    lab

    When IVF Fails

PGS – preimplantation genetic screening can be done on embryos prior to transfer to evaluate chromosomal competence.

Other “genetic causes” of implantation failure

  • Implantation failure is probably caused by other genetic mutations sometimes. With a perfectly normal “karyotype” or chromosome complement.
  • There are tens of thousands of genes in the human genome. A lot of places where something can go wrong.
  • With time there will be genes discovered that are crucial for efficient embryo implantation. These will be both on the embryo side and on the uterine side. Perhaps they will involve the immune system as well.

INFERTILITY treatment involves commitment that is significantly financial, physical, psychological and time consuming. Male infertility treatment for general sexual problems or lack of healthy sperm at Susannah Makram Clinics use advanced male fertility diagnostics to outline effective treatment protocols for couple to choose from. Tests identify and support improvement for (normal sperm count and) poor sperm quality.

Your Naturopathic Portfolio to improve sperm quality at Susannah Makram Clinics supports ICSI if used in an IVF cycle as described.
FIND OUT MORE ABOUT FERTILITY TREATMENT ROUTES AND HOW SUPPORTING LIFESTYLE CHANGES CAN HELP COUPLES TODAY.

Female fertility continued 

What affects fertility?

Total fertility rate

Nutrition for fertility and pregnancy is included in our functional approach to male and female fertility nutrition. We treat with care for the individual and also the couple, at Susannah Makram Clinics

What 5 Factors affect fertility?

Total fertility rate – What affects fertility?

1. Poor nutrition is the biggest factor that affects fertility. Nutrition during pregnancy is seen by measurements taken of a growing a healthy baby. 4 to 6 months before trying to conceive couples are building the foundation. A woman’s body is ready to provide a nourishing environment for growing a baby.

The 9 months of pregnancy are now considered by a lot of researchers to be the most consequential period of our lives. Before we are even born, this time is most important in determining our health for the rest of our life.   [tweetthis]Before we’re even born, this time is most important in determining lifetime #health [/tweetthis]

Babies that are born at a low birth weight, which is primarily determined by maternal nutrition, have a significantly higher risk for diseases. These disease include heart disease, diabetes, hypertension, kidney disease. Later in life the risk for these diseases rises independently of lifestyle risk factors.

For healthy sperm

Obesity in men affects fertility because accumulation of fat in the thighs increases the temperature of the scrotum. This in turn adversely impacts sperm quality. Infertile men have lower concentrations of DHA and EPA in their sperm. They are unlikely to be eating eating enough of the long chain omega-3 fats.

2. This is followed closely by stress

Moura-Ramos, M., Gameiro, S., Canavarro, M., Soares, I. and Santos, T. (2012). The indirect effect of contextual factors on the emotional distress of infertile couples. Psychology and Health, 27(5), 533-549. (10.1080/08870446.2011.598231) 
Barnea ER, Tal J. Stress-related reproductive failure. J In Vitro Fert Embryo Transf. 1991 Feb;8(1):15–23.

50% of infertility is caused by male factors. Oxidative stress is caused primary by excess intake of industrial seed oils, stress and lack of physical activity can damage sperm quality.

The biggest factor keeping women from getting pregnant is the modern lifestyle and it is a big problem because already 1 in 7 women have trouble conceiving. A study out of the UK that suggested that this number could rise to 1 in 3 by 2020. 

What affects fertility?

What affects fertility?

What affects fertility? Other Factors:

3.  Environmental toxins – there are a lot of toxins that end up being endocrine disrupters. These throw the hormones out of whack and that makes it difficult for women to get pregnant.

4.  Medications like birth control – A medical term has been coined Post Birth Control Syndrome  or ‘post-pill amenorrhea’

In some women, it may take some time for their menstrual cycle (and subsequently their fertility) to return to normal when they stop taking birth control pills. The main symptom is a rather obvious one. A woman is unable to conceive even after she has discontinued the use of the birth control pill. Generally speaking, your period should resume within three months. If you have a history of irregular periods and took the pill to regulate your cycle, you may not have a period for many months after you stop taking the pill. If you do not have a period within 6 months, you should see your doctor to determine the cause.

What affects fertility?

5. Medications that affect hormones, metabolism, and synthesis i.e. modern lifestyle  

50% of infertility is caused by male factors. Men should be testosterone dominant not oestrogen dominant and oestrogen dominance in men leads to hypogonadism and infertility. The lower the sperm count and the poorer the sperm quality, the longer it will take to get pregnant. The omega6/omega3 balance is probably one of the biggest factors in male infertility.

What is fertility?

What is fertility?

Side effects of long-term NSAID usage. Long term use or a high dosage of NSAIDs, such as ibuprofen or aspirin, can make it more difficult for you to conceive. Medicines used for chemotherapy (a treatment for cancer) can sometimes cause ovarian failure. This means your ovaries will no longer be able to function properly. Ovarian failure can be permanent.

Side effects of spironolactone. Fertility should recover around two months after you stop taking spironolactone for fluid retention.

Side effects of Neuroleptic medicines. Neuroleptic medicines are antipsychotic medicines often used to treat psychosis. They can sometimes cause missed periods or infertility.

SpermComet Results Guide

DNA in sperm

Paint a clearer fertility profile picture with the SpermComet test. HOW? Measuring sperm DNA damage in individual sperm using the most sensitive test.       [tweetthis]SpermComet: most sensitive test that can measure sperm DNA damage in individual sperm [/tweetthis]
We’re probably all familiar with with the term SPERM COUNT that deals with the quantity of sperm. However, what most of us know less about is SPERM QUALITY.

For couples trying for a baby, when it comes to sperm quality, conventional semen analysis tells us little. One in Four couples in the Uk have difficulty starting a family. The Sperm DNA test may help guide couples. Don’t wast time. Find out if it’s worthwhile taking this test – the most sensitive of its kind – contact us 0207-060-3181

If you’ve already been trying for a baby, or even just starting to think about it, measuring sperm DNA damage in individual sperm paints a clearer fertility profile picture:  [tweetthis]Trying for a baby, or starting to think about it? See your fertility profile clearly[/tweetthis]

<25% Damage = Sperm DNA damage is not the major cause of infertility Damage

>25% Damage = Sperm DNA damage is a cause of infertility

-> Refer to fertility clinic

25-49% Damage = Sperm DNA damage is a cause of infertility

-> Lifestyle Changes + Antioxidants
-> IVF may be the best option

>50% Sperm DNA Damage

-> Lifestyle Changes + Antioxidants
-> ICSI may be the best option

>50% Sperm DNA Damage & Failed ICSI

-> Lifestyle Changes + Antioxidants
-> Testicular Biopsy may be the best option
-> Alternatively ICSI with donor sperm may be considered

ICSI – Intra-cytoplasmic Sperm Injection – is the most successful form of treatment for men who are infertile and is used in nearly half of all IVF treatments (HFEA 2010). ICSI only requires one sperm, which is injected directly into the egg. The fertilised egg (embryo) is then transferred to your uterus (womb) (HFEA 2009a)

 One in six couples has difficulty having a baby: in 40 per cent of these cases, the difficulty is associated with the man.

Susannah2

When it comes to sperm, not talking about it means many couples trying for a baby may be missing out on information that could improve their chances… information that could help reduce the loss of valuable time and financial costs and – not least – the emotional heartache that can be hardest of all.

When IVF fails it’s a frustrating situation for couples and their fertility doctors. Sperm DNA Fragmentation Testing results can help be a guide for couples.

Gut Microbiome and Fertility

Gut Microbiome and Fertility

Recap then gut microbiome and fertility. The human microbiome consists of the microbes living on and within our human bodies. Most of these bugs inhabit our large intestine. There, a few pounds’ worth of bacteria, yeasts, archaea and even viruses. These help digest food, calibrate our metabolic and immune function and hold off would-be invaders.

There’s growing evidence that the pathogenic effects of bacterial vaginosis may not be confined to the lower genital tract.

Fertility Nutrition

Most studied is how gut microbiota affects an individual’s risk of obesity and other metabolic conditions. In both men and women weight management plays a pivotal role in reproductive heath, pre conceptual care, without and throughout use assisted reproductive technologies.      [tweetthis]In men & women weight management is crucial to reproductive heath, pre-conceptual care[/tweetthis]

Much more attention should be paid to the impact of obesity on fertility in both women and men. This appears to be particularly important for women before assisted reproductive technologies are used. Treatment of obesity may improve androgen imbalance and erectile dysfunction, the major causes of infertility in obese men.

Gut Microbiome and Fertility

Gut Microbiome and Fertility

Female Fertility – The Vaginal Microbiome

A special subset is the vaginal microbiome. The vaginal microbiome inhabits the vagina and successful reproduction, as it turns out, owes an immense debt to this microbial community.

A healthy vaginal microbiome produces lactic acid and hydrogen peroxide. These maintain a level of acidity that keeps troublemaking microbes at bay. When the vaginal community becomes unbalanced, on the other hand, acidity decreases. The wrong microbes may then invade or, if they’re already present, bloom. How does this happen?

The Role Of The Vaginal Microbiome In Fertility – Reproductive Health & Beyond

This disturbance can cause bacterial vaginosis—not really an infection, but an out-of-whack ecosystem. It sounds like a trifling problem, and half of women with vaginosis may display no obvious symptoms. But this minor-seeming imbalance can have major consequences.

Vaginosis increases the risk of contracting secondary infections, from herpes to HIV. But even on its own, the microbial shift may prompt low-grade inflammation that can derail reproduction. It can prevent fertilisation in would-be mothers, prompt spontaneous abortion in pregnant women, and increase the risk of preterm birth later in pregnancy.

Many factors affect the vaginal ecosystem—smoking, stress, diet, the number of sexual partners, and obesity. One of the most direct ways to upset the vaginal microbiome may be douching.

The Role Of The Vaginal Microbiome In Fertility – Bacterial Vaginosis & Miscarriage

The consequences of bacterial vaginosis can be devastating. In a study of 1,950 urban women in Philadelphia, for example, vaginosis in the first trimester more than doubled the risk of spontaneous pregnancy loss in the second. In Belgium, vaginosis more than quintupled the risk of early preterm birth.

Vaginosis-related microbes have been implicated in roughly one-quarter of all preterm births. For the most vulnerable group of children, those born extremely preterm, or before 25 weeks, the number perhaps doubles.
Studies in Kuopio Finland by this Finnish group have since replicated the finding among 15-to-17-year-olds, implying that the consequences of prenatal inflammation persist into adolescence and probably adulthood.

Does the vaginal microbiome play a role in IVF?

personalised nutrition

personalised nutrition

                                                     

Influence of bacterial vaginosis on in-vitro fertilisation and embryo implantation during assisted reproduction treatment.

Although an altered vaginal microbiota has been demonstrated to affect parturition, its role in assisted reproductive technologies is uncertain.
Clinical findings suggest that routine screening for bacterial vaginosis in the hope of improving the success of IVF treatment is not justified. The prevention of complications in pregnancy associated with bacterial vaginosis might be a more relevant indication for screening at the time of IVF treatment, in particular patients with tubal disease, if treatment were shown to be effective for that particular purpose. However, antibiotic treatment before IVF has been shown to be positively disadvantageous for IVF by encouraging other organisms.

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