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Posts Tagged ‘nutrigenetics’

DNA Methylation Epigenetics

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DNA Methylation Epigenetics

Are our genes making us fat? Do we inherit chronic skin conditions & hair loss? DNA Methylation Epigenetics Our DNA contains instructions for building all parts of our body. So, although genetic polymorphisms predispose us to developing a certain health condition, epigenetics or how our environment impacts our genes plays a larger role in the development of a chronic condition such as eczema. 1) 2)

  • The DNA in our bodies is wrapped around proteins called histones.
  • Both the DNA and histones are covered with chemical tags. This second layer or structure is called the Epigenome.
  • The epigenome shapes the physical structure of the genome. It tightly wraps inactive genes making them unreadable. It relaxes active genes making them easily accessible.
  • Different sets of genes are active in differential types.
  • The DNA code remains fixed for life but the epigenome is flexible.
  • Epigenetic tags react to signals from the outside world such as diet and stress. The epigenome dynamically responds to the environment. Stress, diet, behavior, toxins, and other factors regulate gene expression.
  • The epigenome adjusts specific genes in our genomic landscape that responds to our rapidly changing environment.
DNA methylation epigenetics

DNA methylation epigenetics

Our body is a system, an ecosystem where everything is connected. When that system is out of balance, diseases arises.

Nutrigenomics teaches us how to prevent, treat and reverse almost every chronic illness. Chronic disease include diabetes, high blood pressure, depression, allergies, asthma, IBS, reflux, migraines, acne, low sex drive, fatigue and more.

Disease goes away as a side effect of getting healthy. When we treat the cause or causes with proper understanding of these processes that led to the disease, then we’re going to change. We won’t accept that simply living with certain conditions is acceptable.

Immune Modulation and Chronic Inflammation

Chronic inflammatory disorders such as eczema, acne and psoriasis – skin conditions – are characterised by a hyper responsive immune system.  10 key epigenetic factors must be addressed to regulate and better coordinate our immune response.

1.  Blood Sugar instability  Blood sugar imbalances cause immune dysfunction and malcoordination.  Stable blood sugar is critical for a healthy immune response.

2.  Low Vitamin D Levels Individuals with low vitamin D3 levels (below 40 ng/ml) are at significant risk for developing chronic inflammation and allergy-like conditions 3)

3.   Gut Dysbiosis  Unhealthy microbial imbalance in the gut microbiome leads to leaky gut syndrome and chronic inflammation 4) so we’ve got to address gut issues in order to get well.

4.   Mitochondrial Dysfunction  The mitochondria are the energy producing organelles in each cell of the body.  They are extremely key in the bodies ability to handle oxidative stress.  Dysfunction in the mitochondria leads to increased free radical and oxidative stress which creates immune alterations. Low Glutathione Levels. Glutathione is the major antioxidant within every cell of the body.  It’s critical for white blood cell (WBC) function as the WBCs encounter tremendous amounts of free radical and oxidative stress every second of the day. Low glutathione leads to chronic inflammation and often to auto-immunity 5).

6.  Methylation. Methylation is a key process that protects DNA, turns on and off genetic traits and helps to detoxify environmental chemicals.  Many of us individuals have certain genetic polymorphisms that limit their ability to appropriately methylate. Methylation plays a very important role in T cell function and poor methylation status is associated with the development of autoimmunity. Psoriasis is a T cell mediated inflammatory skin disease. 6)  Poor Omega 6:3 ratio  – the average person has significantly more omega 6 fats than omega 3 fats.  The increased omega 6 stimulate the release of pro-inflammatory mediating prostaglandin molecules.  This is a key factor in the development of chronic inflammation and skin related disorders 7).



7.  Environmental Toxins:  Exposure to high levels of infectious microbes, environmental chemicals, pesticides, herbicides, beauty, hygiene and other personal care products, heavy metals and biotoxins e.g. mold. These wear down our body’s glutathione levels, alter the gut microflora and increase inflammatory activity in the body (7, 8, 9).

8.  High Stress High mental and emotional stress increases stress hormone production. This changes our posture and the way we breathe, which in turn induces inflammatory activity within the body. Poor posture, breathing and musculoskeletal aches and pain that result can simulate chronic mental and emotional stressors 10)

9.  Lack of Sleep Poor quality sleep promotes immune dysfunction and increased inflammation throughout the body. Good sleeping habits and optimal melatonin secretion reduce inflammation and promote improved tissue healing 11).

10.  EMF Exposure  Electromagnetic frequency exposure has been shown to alter the function of the immune system. Also, its been shown to increase one’s susceptability to developing an auto-immune condition 12)

DNA Nucleotides

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DNA Nucleotides

Nucleotides are nutritional building blocks. They’re involved in all cellular activity and metabolic processes. Nucleotides are also building blocks of DNA and RNA.

WHAT DOES THIS MEAN EXACTLY? We can examine their function regarding accelerated signs of ageing and weight loss.

Nucleotide Nutrition

Our bodies must create new cells to continue living. Cell division is an important part of this process. With the help of nucleotides and RNA a typical cell divides, ‘unzipping’ the DNA and creating two new cells. For example, in an adult human, millions of cells divide every second just to maintain the body!

DNA nucleotides

DNA nucleotides

DNA Nucleotides –  the best supplements

Why take nucleotide supplements when we have dietary nucleotides?

[tweetthis]How well are nutrients surviving your digestion? [/tweetthis]Interrelations between constituents in foods are significant. This significance is dependent on:
1) The balance between constituents within the food. i.e. Nutrients can affect each other’s absorption.
2) How well these constituents survive digestion.
How well are nutrients surviving your digestion? [tweetthis]How well are nutrients surviving your digestion? [/tweetthis]
3) The extent to which these constituents in our food appear biologically active at the cellular level. i.e. the effect of a
large intake of a particular nutrient may vary depending on whether it’s taken in concentrated form or as part of a whole

Read more about this operational food synergy in this study from the 2009 American Society of Nutrition.

As humans we’re adapted to getting our nutrients from whole foods. Most nutrients needs enzymes, synergistic co-factors and organic mineral-activators to be absorbed properly.     [tweetthis]Most nutrient absorption relies on enzymes, synergistic co-factors, mineral-activators[/tweetthis]   While these are naturally present in foods, they are often not included in synthetic vitamins with isolated nutrients.

Being important for growth, nucleotides are also present in human breast milk. In healthy people, dietary nucleotides are probably not essential, however, under certain circumstances dietary nucleotides may help. This is because nucleotides optimise the function of the gastrointestinal and immune systems. In other words, supplementary nucleotides help the body produce cells rapidly as required during times of stress and when it is challenged by infection or disease. At these times the body’s requirement for nucleotides from dietary sources is much greater. Some of our diets can be nucleotide deficient.

However, although nucleotides can be found in some food sources,  soil-depletion, genetic-modification, and more have decreased the amount of nutrition in our foods.

mineral depletion

Dietary Nucleotides

Our modern diets often mean we don’t eat enough of the foods that are rich in nucleotides such as offal and tripe. Dietary sources of nucleotides are found to varying degrees in many foods – lamb, liver. Vegan nucleotides or vegetarian nucleotides can be fund in mushrooms (but not fruit and other vegetables). These are all are rich in nucleotides.

NOTE: There are a couple of contraindications for taking nucleotides as supplements. Because of its purine content, those of us who are genetically predisposed, have a history of, or suffer from gout are generally advised not to supplement nucleotides. Furthermore, the strong immune-enhancing effect prohibits the use of nucleotides for sufferers of auto-immune diseases and users of immune-repressive medications.

Nucleotides May Help IBS

Irritable Bowel Syndrome IBS is a chronic disorder affecting an estimated 15 – 22% of western populations. Animal work shows that villi height and crypt depth in the intestine is increased as a result of dietary nucleotides Statistik beratung.
Dietary nucleotides may be semi-essential under conditions of ill-health, poor diet or stress See study.
Dietary nucleotide supplementation may improve some of the symptoms of IBS above baseline and placebo level – See Study.

Nucleotides and Immunity

When infected with the Flu millions of viruses invade our body. These need to be destroyed in order to regain normal health. It therefore becomes crucial that our bodies have the availability of sufficient nucleotides to rapidly and efficiently respond buch schreiben lassen. Nucleotides response by producing enough new white blood cells to overcome the infection. If the nucleotide supply is insufficient, the Flu viruses will proliferate unhindered ghostwriter österreich. This may lead to more severe symptoms and prolonged illness. Conversely, with enough nucleotides the infection can be quickly counteracted during its initial stages.

Nucleotides also help gut mucosal defence, which is also part of the immune system.

Nucleotides aren’t yet considered essential nutrients for humans. However, stress, physical exertion, illness, poor diet and the excessive use of antibiotics and alcohol increase our need for nucleotides ghostwriter. This is to aid timely and effective cell proliferation.  Many infant formulas now contain nucleotides because studies have shown that babies fed nucleotide-supplemented infant formula experience better growth and development. The infant also maintains a healthier immune system with increased levels of beneficial intestinal bacteria. This reduces gastrointestinal distress.

In adults, advantageous effects were found in markers of immune function: i.e. salivary immunoglobulin-A (sIgA), which is involved in the first defence against coughs and colds Google Agentur. Cells of the immune system, gastrointestinal cells and blood cells lack the potential to synthesise nucleotides themselves.

DNA Nucleotides: nucleotides do not stimulate innate or acquired immunity. Rather, they provide the resource for unhindered cell proliferation, gene expression and response to special environmental and physical challenges.

Safe, clinical, practical and effective.

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